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Research List - Current Projects

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The following projects are undertaken in the research area of Neuroscience

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Reactive and regenerative alterations underlying the neuronal response (Doctorate)

Supervisors: James Vickers  Members: Jyoti Chuckowree
Mature CNS neurons may attempt to regenerate following trauma. Cytoskeletal reorganisation is crucial to neuronal recovery following injury. I aim to characterise the reactive and regenerative cytoskeletal alterations that underlie the neuronal response to injury. I will also investigate agents that may prevent maladaptive attempts at regeneration.

a-, b-,and g-synuclein: developmental localisation and response to injury in neurons and glia. (Doctorate)

Supervisors: James Vickers
a-synuclein is a component of the pathological inclusions of many neurodegenerative diseases. They are abundant proteins found in the CNS, associated with synapse development and maintenance. I am investigating the developmental localisation of a-, b- and g-synuclein in primary cell cultures with various forms of cellular insult.

The neural reaction to injury: Clues to the cause and prevention of acquired brain damage and Alzheimer's disease (Staff)

 Members: James Vickers
Funded by National Health & Medical Research Council - Fellowship Research

The neural reaction to injury: Clues to the cause and prevention of acquired brain damage and Alzheimer's disease (Staff)

 Members: James Vickers
Funded by National Health & Medical Research Council - Grant - 5 year project

a - Synuclein: a Possible Therapeutic Target for Inhibiting the Neurodegeneration of Parkinson's Disease (Staff)

 Members: James Vickers
Funded by Royal Hobart Hospital Foundation - Research Trust Grant

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