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Research Area Details

Vanilloid Research Group

Substance P (green) and NK1 receptor (receptor)

Research Overview

The group’s research centers on the pharmacology of the sensory neuron stimulant and toxin, capsaicin, and several related vanilloids, including resinferatoxin. Vanilloids and vanilloid antagonists have therapeutic implications in the treatment of pain and a variety of (currently) poorly treated disorders such as hyperactive bladder. Projects include basic studies into the regulation of vanilloid receptors in the central nervous system and peripheral tissues, the effects of vanilloid ingestion (in the form of chilli) on cardiovascular risk factors and the potential role of vanilloid receptors in immune dysfunction in dialysis patients.

Current Collaborators


Professor Madeleine Ball School of Human Life Sciences
Dr Kiran Ahuja School of Human Life Sciences
Assoc Prof Dominic Geraghty School of Human Life Sciences
Dr Iain Robertson School of Human Life Sciences
Dr Cecilia Shing School of Human Life Sciences
Professor Rob Fassett Launceston General Hospital
Assoc Prof Jeff Coombes University of Queensland

Methods

The laboratory is well resourced to conduct a variety of techniques.

Funding

Present and past funding from UTas, NHMRC and Clifford Craig Medical Research Trust.

Link to Publications and Current Projects (via WARP): (http://rmdb.research.utas.edu.au/public/rmdb?indiv_detail_warp_trans+265)

Other Links

Contact

For further information on current and/or future projects, please contact Assoc Prof Dominic Geraghty(email: D.Geraghty@utas.edu.au, or phone: +61 3 6324 5483).